microRNA‑200a functions as a tumor suppressor by targeting FOXA1 in glioma
نویسندگان
چکیده
منابع مشابه
microRNA-29a functions as a tumor suppressor in nasopharyngeal carcinoma 5-8F cells through targeting VEGF
Objective(s): microRNA-29 (miR-29) family miRNAs have been mentioned as tumor suppressive genes in several human cancers. The purpose of this study was to investigate the function of miR-29a in nasopharyngeal carcinoma (NPC) cells. Materials and Methods: Human NPC cell line 5-8F was transfected with mimic, inhibitor or scrambled controls...
متن کاملMicroRNA-326 Functions as a Tumor Suppressor in Glioma by Targeting the Nin One Binding Protein (NOB1)
Malignant glioma is the most common type of primary brain tumor in adults, characterized by rapid tumor growth and infiltration of tumor cells throughout the brain. Alterations in the activity of the 26S proteasome have been associated with malignant glioma cells, although the specific defects have not been identified. Recently, microRNA-326 (miR-326) was shown to play an important role in glio...
متن کاملMiR-433 functions as a tumor suppressor in glioma cells by regulating YAP1
YAP1 is an oncogene in plenty types of tumors and miR-433 is a tumor suppressor in many types of tumors. Furthermore, YAP1 is overexpressed in glioma and the function mechanism is still not entirely clear. So this study was aimed to investigate whether YAP1 expression in glioma is associated with miRNA. The YAP1 expression in glioma tissues and glioma cells and miR-433 expression in glioma tiss...
متن کاملMicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A
MicroRNAs (miRNAs) are endogenously small non-coding RNAs which are key post-transcriptional regulators of gene expression. Deregulation of miRNAs is common in human tumorigenesis. We report that miRNA-205 is significantly down-regulated in glioma cell lines and tissue specimens. Ectopic expression of miRNA-205 induces apoptosis, cell cycle arrest...
متن کاملMicroRNA-409-3p functions as a tumor suppressor in human lung adenocarcinoma by targeting c-Met.
BACKGROUND/AIMS Dysregulation of microRNAs is correlated with tumor development. The aim of this study is to investigate the clinicopathologic and prognostic significance of microRNA (miR)-409-3p and its tumor suppressor roles in lung adenocarcinoma (LAD). METHODS Quantitative real-time PCR (qRT-PCR) was performed to detect miR-409-3p expression in LAD tissues and corresponding noncancerous t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2018
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2018.6895